Impact of supplementing newborn infants with vitamin A on early infant mortality: community based randomised trial in southern India

Impact of supplementing newborn infants with vitamin A on early infant mortality: community based randomised trial in southern India

This article assesses the impact of supplementing newborn infants with vitamin A on mortality at age six months. The study was a randomised, placebo controlled, community based trial conducted between June 1998 and March 2001 in two rural districts of Tamil Nadu, southern India.

Key results include:

  • Infants in the vitamin A group had a 22 per cent reduction in total mortality (95 per cent confidence interval four per cent to 37 per cent) compared with those in the placebo group.
  • Vitamin A had an impact on mortality between two weeks and three months after treatment, with no additional impact after three months.
The paper concludes that supplementing newborn infants with vitamin A can significantly reduce early infant mortality.
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