Packages of care for dementia in low- and middle-income countries

M.J. Prince;D. Acosta;E. Castro-Costa;J. Jackson;K.S. Shaji / Public Library of Science Medicine , 2009

Two-thirds of people with dementia live in low- and middle income countries (LMICs), where there are few services available and levels of awareness is low.  This paper focuses on the effective ma...

Grand challenges in global health: engaging civil society organizations in biomedical research in developing countries

Anant Bhan;Jerome A. Singh;Ross E. G. Upshur / Public Library of Science Medicine , 2007

While several publications have addressed the role of civil society organisations (CSOs) in social science research in health, their role in biomedical research has not been widely discussed. This ...

A Breakthrough in R&D for neglected diseases: new ways to get the drugs we need

Mary Moran / Public Library of Science Medicine , 2005

Whereas only 13 new drugs have been developed for neglected tropical diseases since 1975, this paper, published in PLoS Medicine, notes that this is as a result of current perception that these diseas...

Does male circumcision prevent HIV infection?

N. Siegfried / Public Library of Science Medicine , 2005

Given the devastating mortality and morbidity associated with HIV and AIDS, many potential prevention measures against HIV infection have been explored. Male circumcision is one of these. This short a...

The unfinished public health agenda of Chagas disease in the era of globalization

C. Franco-Paredes;M.E. Bottazzi;P.J. Hotez / Public Library of Science Medicine , 2009

In Latin America, Chagas disease (CD), caused by infection with Trypanosoma cruzi, is a prime example of an co-evolutionary process in which parasites and mammalian reservoirs (including humans) ar...

Complexities of assessing the disease burden attributable to Leishmaniasis

C. Bern;J.H. Maguire;J. Alvar / Public Library of Science Medicine , 2008

Among parasitic diseases, morbidity and mortality caused by leishmaniasis are surpassed only by malaria and lymphatic filariasis. This article from The Public Library of Science shows how the estim...

Neglected disease research and development: how much are we really spending?

M. Moran;J. Guzman;A.-L. Ropars / Public Library of Science Medicine , 2009

Specific research and development (R&D) investment data are available for some neglected diseases but these cannot readily be compared since each survey uses different methodologies and covers dif...

Influence of rapid malaria diagnostic tests on treatment and health outcome in fever patients, Zanzibar - a crossover validation study

M. I. Msellem;A. Martensson;G. Rotlant / Public Library of Science Medicine , 2009

Malaria continues to impact significantly on the lives of persons from regions where the disease is present. While major gains have been made in the development of anti-malarial medications for the tr...

Access to health care in contexts of livelihood insecurity: a framework for analysis and action

B. Obrist;N. Iteba;C. Lengeler / Public Library of Science Medicine , 2007

This paper highlights the increasing need for providing high quality goods and service delivery in health care in resource-poor settings, especially in Africa. It further suggests additional effort...

Strategies for aspiring biomedical researchers in resource-limited environments

P Garcia;W Curioso / Public Library of Science Medicine , 2008

This article, published in PLoS Neglected Tropical Diseases, looks at how biomedical researchers from developing countries can conduct research in resource poor settings....